What vitamin deficiency would cause an overy high level of pyruvate in a patients blood and urine?
June 25, 2009 by Supplements and Vitamins Tips
Filed under Vitamins & Antioxidants
Can you answer ask m’s question about Supplements?:
Suppose you found an overly high level pyruvate in a patient’s blood and urine. One possible cause is a genetic defect in the enzymes pyruvate dehydrogenase, but another plausible cause is a specific vitamin deficiency. Explain what vitamin might be deficient in the diet and why that would account for high levels of pyruvate to be excreted in the urine. How would you determine which explanation is correct?
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Suppose you found an overly high level pyruvate in a patient’s blood and urine. One possible cause is a genetic defect in the enzymes pyruvate dehydrogenase, but another plausible cause is a specific vitamin deficiency. Explain what vitamin might be deficient in the diet and why that would account for high levels of pyruvate to be excreted in the urine. How would you determine which explanation is correct?
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Supplements Feedback: Vitamin B1 deficiency. It is required for transformation of pyruvic acid to acetyl CoA. Vitamin B5 is required for formation of acetyl CoA, also. I guess you could take vitamin B supplements and see if the condition improves. if not, then it would be a PDK enzyme problem.